Brain white matter connection strength positively associated with movement speed during Archimedes spiral tracing task

Research by Sarah Cote¹, Marit Ruitenberg², Jos van der Geest³, Kevin Duff⁴, and Vincent Koppelmans⁵

¹Yeshiva University, New York, NY, US; ²Leiden University, the Netherlands; ³Erasmus University Medical Center, Rotterdam, the Netherlands; ⁴Oregon Health and Science University, Portland, OR, US; ⁵University of Utah, Salt Lake City, UT, US

The image below shows brain white matter connections, for which the connection strength is significantly (p < 0.05, corrected for multiple comparisons) positively associated with movement speed during an Archimedes spiral tracing task. The data are from a combined sample of 68 cognitively unimpaired older adults, 44 individuals with amnestic mild cognitive impairment, and 34 individuals with Alzheimer's disease. The line thickness indicates the extent of significance (thicker = more significant). The line color indicates the effect size in Z-score (see also the color bar). The brain imaging data is based on diffusion MRI data. Data processing and analysis was conducted on CHPC resources.

Attribution: This content was provided by researchers involved with the project and edited by staff at the CHPC.