The Utah PRISMS Ecosystem: An Infrastructure for Global Exposomic Research

By Ramkiran Gouripeddi^1,2, Mollie Cummins^1,2,3, Julio Facelli^1,2, and Katherine Sward^1,2,3 

¹Department of Biomedical Informatics, ²Center for Clinical and Translational Science, ³College of Nursing, University of Utah

The Utah PRISMS (Pediatric Research Using Integrated Sensor Monitoring Systems) Team uses a systematic approach to aggregate data on environmental exposures and socio-economic factors to explore potential effects of the modern environment on health. The project uses sensor measurements and information from individuals in the community to support research at both the population and personal level. It supports a standards-based, open source informatics platform to meaningfully integrate sensor and biomedical data and consists of:

1. Data Acquisition Pipeline: Hardware and software, wireless networking, and protocols to support easy system deployment for robust sensor data collection in homes, and monitoring of sensor deployments.
2. Participant Facing Tools: Annotate participant generated data, display sensor data, and inform participants of their clinical and environmental status.
3. Computational Modeling: Generate high resolution spatio-temporal data in the absence of measurements as well as for recognition of activity signatures from sensor measurements.
4. Central Big Data Integration Platform (OpenFurther): Standards-based, open-access infrastructure that integrates study-specific and open sensor and computationally modeled data with biomedical information along with characterizing uncertainties associated with these data.
5. Researcher Facing Platforms: Tools and processes for researchers performing exposomic studies of a variety of experimental designs.

System Status

Cluster Utilization